As a former Chairman of the AGNT, a former director of the GERA Board and a member of RIAC, it is a pleasure to file in this annual national GEM report. Israel is one of the ten countries that established the GEM International Research Program in 1998, and since then it has participated in it continuously. In 2019/2020, 50 countries participated in the study. At present, the entire world and Israel face the challenges of the Covid-19 pandemic, which appears to be significantly affecting world economy and is expected to change the way countries approach entrepreneurship and innovation. The government of Israel and other governments consider entrepreneurship and innovation as the means for overcoming national and personal crises. It is noted that the national and international study team is completing the development of a methodology that will enable to study the effects of the pandemic on relevant phenomena and translate them into objectives for the 2020-2021 study. The GEM study in Israel is conducted at the Ira Center for Business, Technology and Society, Ben-Gurion University, which provides academic and economic sponsorship. The Agency for Small and Medium-Sized Businesses of the Ministry of Economy and Industry, Government of Israel, has been supporting the study for many years.